A Method to Improve Memory and Mood by Inhibiting Cell-Surface Expression of Alpha 5 Subunit-Containing GABA-A Receptors

This discovery is a unique technique for treating memory and mood disorders. The method is comprised of the administration of a compound that inhibits the protein-protein interaction. These compounds can be used to treat or prevent disorders associated with increased alpha 5 GABA-A receptor function such as memory and mood disorders associated with inflammation or after general anaesthesia.