License U of T Technologies

Who is this for?

Industry and other parties interested in licensing or otherwise using University of Toronto (U of T) technologies or working with spinoff companies based on U of T intellectual property.

What do I need before I can begin?

No information is required to begin. If you have questions regarding licensing University of Toronto (U of T) technologies or working with our spinoff companies, please reach out to the Innovations & Partnerships Office: Director, Innovations at 416-946-5515.

Technology Licensing & Startup Opportunities

The University of Toronto (U of T) is a global leader in turning research into products, services, companies and jobs. The Innovations & Partnerships Office (IPO) is your one-stop-shop to license these technologies or work with spinoff companies based on U of T intellectual property (IP). IPO’s team of technology transfer professionals make the process as quick and easy as possible.

Use the Technology Explorer below to discover market-ready innovations and companies based on U of T IP or contact us to find custom solutions.

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In the last 5 years, companies emerging from U of T Research have secured more than $1.5 billion in investment and capital. We're #1 in Canada for research-based startups and our ecosystem is among the top 10 university-managed incubators in the world.

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Technology Explorer

Technology Keywords
Peptide Therapeutic for Parkinson’s Disease Therapeutics
Therapeutic Targeting of a Novel Gene Product in Inflammatory Bowel Disease Inflammatory bowel disease, IBD, Therapeutics, Small Molecules, Crohn's disease, Colitis
Probiotics to Prevent Dental Cavities Probiotic, Therapeutics
Determining Protein-Protein-Interactions for Target Identification and Drug Screening Drug Target Identification
Cancer Treatment Guidance Using F-box or Cyclin Biomarkers Diagnostics
Kidney-On-A-Chip Model with Glomerular Structural Features Organ-on-a-chip
Toronto Annotation Suite: AI-Powered Data Annotation 3D imaging, Artificial Intelligence (AI), Automotive, Companies, Computer Graphics, Computer Vision, Data Analytics, Deep Learning, Human-Computer Interaction, Image and video processing, Neural Networks, Object Annotation, Software
AI-Powered Platform for Better Decision Making Software, Deep Learning, Data Analytics, Aerospace, Computer Graphics, Machine Learning, Digital Twin, Companies
Biocompatible Microemulsions as Delivery Systems for Poorly Water-Soluble Active Ingredients Drug Delivery System
Method and model for simulating stepwise undirected network growth Smart Cities, Software, Biotechnology, Construction
Active shading devices for building facades Climate Change, Construction, Microfluidics, Environment, Smart Cities
Improvements to Organ-on-a-Chip Device Architecture Organ-on-a-chip
Monte Carlo Lights: A model-based reinforcement learning approach to Adaptive Traffic Signal Control Machine Learning, Automotive, Deep Learning, Software, Traffic, Smart Cities
Novel Compounds for Drug-resistant NSCLC Treatment Identified using a Novel Assay Therapeutics, Screening
HippoCamera: Digital Memory Augmentation Advanced Health Technologies, Artificial Intelligence (AI), Cameras, Communications, Companies, Digital Media, Health & Related Life Sciences, Image and video processing, Learning and Memory, Mobile Apps, Neurological Disorders, Smartphones, Software
Software Enabling Automatic Self-Calibration of Robots Calibration, Manufacturing, Robotics, Sensors & Instrumentation, Software
Spruce Tree Crown Delineation using a Novel Algorithm Algorithm
Engineered Chondroitinase ABC for Treatment of Traumatic Injury to the CNS Therapeutics, CNS
Nanostructured Solar Selective Catalytic Supports Climate Change, Energy, Nanomaterials and Nanoparticles
Nanostructured Metal Oxides Compositions for Applied Photocatalysis Carbon capture and sequestration, Climate Change, Fossil fuels, Nanochemistry
An Injectable Hydrogel for Delivery of Therapeutics for Osteoarthritis Drug Delivery, Osteoarthritis
Design of Short Promoters for Gene Therapy gene therapy, Therapeutics, Virus
Agonists for GPR55 as Multi-Disease Targets Drug, Therapeutics, Small Molecules, GPCR
Adaptive Neural Implant for Modulation and Observation (ANIMO) Advanced Health Technologies, Wearable Tech, Machine Learning, Battery, Electrical and Computer Engineering, Circuit design, Medical Implants and Prosthetics, Medical Devices
Tunable Activation of Gene Expression for Therapeutic Use Therapeutics, Drug, Platform
Targeted Protein Degradation using Novel E3 Ligases Therapeutics, Drug
Smart Traffic Control Software Powered by Machine Learning Automotive, Software, Machine Learning, Traffic, Smart Cities, Deep Learning
Color Sandbox: Smart Swatch Builder Software, Computer Graphics, Animation, Neural Networks, Deep Learning, Artificial Intelligence (AI), Machine Learning
Autoscribe: AI-Powered Voice Assistant for Clinicians Advanced Health Technologies, Artificial Intelligence (AI), Audio, Communications, Companies, Deep Learning, Health & Related Life Sciences, Human-Computer Interaction, Machine Learning, Natural Language Processing (NLP), Patient Care, Point-of-Care, Software
Rhea: Digital Wellness Platform for Personalized Brain Rehabilitation Advanced Health Technologies, Companies, Concussion, Digital Media, Health & Related Life Sciences, Kinesiology & Physical Education, Mobile Apps, Neurological Disorders, Pain, Sensory Systems & Rehabilitation, Smartphones, Software, Wearable Tech
Deep Learning Performance and Energy Optimization Techniques Artificial Intelligence (AI), Chips, Companies, Computer Hardware, Deep Learning, Electrical and Computer Engineering, Smart Cities, Software
AI-Powered Remote Patient Monitoring Platform Remote monitoring, Advanced Health Technologies, Wearable Tech, Clinical Tests, Health & Related Life Sciences, Software, Companies
Organ-on-a-Chip for Airway Tissue Modelling Organ-on-a-chip, Lung, Airway, Microfluidics, Alveolus, Drug Discovery, Cell Culture, Drug, Cystic Fibrosis, COPD, Device, Organoid, Organ, Respiratory, Pre-clinical testing, Pollutants
Serum-Free Cell Culture Media Design Using an Artificial Intelligence Algorithm Artificial Intelligence (AI), Media, Culture, stem cells, Car-t, Cell growth, Medium, In silico, cells, Neural Networks, Reagents, tissue culture reagents, Manufacturing, Cell manufacturing, Bioreactor, Cell Therapy, Scaleup
A Low-Voltage Ride-Through (LVRT) Method for Grid-Connected Power Electronic Inverters Energy, Electrical and Computer Engineering, Smart Cities, Grid, Power, Energy Systems
Cyber-resilient protection for energy grids Energy, Cybersecurity, Smart Cities, Power, Grid, Energy Systems
Quantum-Safe Communication Communications, Companies, Computer Hardware, Cybersecurity, Electrical and Computer Engineering, Quantum Computing, Encryption
Maturation Medium for Induced Pluripotent Stem Cell-Derived Cardiomyocytes Culture, Media, Medium, Maturation, iPSCs, Induced pluoripotent stem cells, heart failure, Cardiomyocytes, Drug, Efficacy, Disease, Cell Therapy, stem cells
Chemosensors for Detection of Bacteria, Apoptosis, and Phospholipidosis Sensors, Fluorescent sensors, Bacteria, Bacterial detection, Phospholipids, Phospholipidosis, Apoptosis, Excimer, Dye, Detection Methods, Detection, Diagnostics, Negative
Biomarkers for Diagnosis and Prognosis of Heart Failure heart failure, Biomarkers, SFRP-3, Slim-1, Mimecan, IGFBP-7, Nogo-C, Diagnosis, Prognosis, Cardiomyopathy, Blood, Serum, Plasma, Circulation, Troponin, Natriuretic peptide, Proteins, Marker
A Small Molecule Allosteric Modulator of CB1R for Treatment of Psychosis and Schizophrenia Neurological Disorders, Brain, cannabinoid, Receptor, CB1R, dopamine, psychosis, schizophrenia, Drug, Drug Discovery, neurotransmitter, neuron, agonist, allosteric modulator, modulator, inhibitor
ServiceMiner: Transforming process data into actionable insights Data Analytics, Software, Machine Learning
EEG-Based Image Reconstruction Artificial Intelligence (AI), Brain-Computer Interface, Communications, Deep Learning, Health & Related Life Sciences, Medical Implants and Prosthetics, MRI, Neurological Disorders, Research Tools, Software
Closed-loop neurostimulator and signal processing methods Artificial Intelligence (AI), Chips, Computer Hardware, Diagnostics, Electrical and Computer Engineering, Machine Learning, Medical Devices, Medical Implants and Prosthetics, Microelectrodes, Nanotechnology, Neurological Disorders, Seizures
iTest: A modular cloud platform for industrial motor testing Software, Computer Hardware, Motor, Robotics, Automotive
Microfluidic Platform for Uniform Spheroid Growth, Release, and Drug Screening Cancer, High-throughput, Screening, Assay, Cell, Extracellular matrix, Collagen, Hydrogel, Microfluidics, Matrix, Organoid, Spheroid, Drug, Drug Discovery
Point-of-Care Detection of Infectious Disease Using Restriction-Enzyme-Based Reporters Cell Free, Infectious Diseases, Sensors & Instrumentation, Electrochemical Detection, Enzyme, Point-of-Care, POC, mRNA, RNA, Electrode, Microelectrodes, Agriculture, Virus, Bacteria, Bacterial detection, Gene, Circuit
Dynamic, Pixelwise Image Sensing and Systems 3D imaging, Cameras, Circuit design, Computer Graphics, Computer Hardware, Software, Computer Vision, Image and video processing, Semiconductors
pH-Responsive Colloids for Enhanced Drug Delivery Drug Delivery, Drug, Colloids, Endocytosis, Transferrin, Receptor, Cancer, Oncology, Small Molecules, Triggered release, Drug Delivery System, Cytotoxicity, Excipients, Lysosomal, Payload, Membrane
A Drug Delivery Method to Increase Delivery of Nanoparticles to Cancer Tumours Nanoparticle, Nanomaterials and Nanoparticles, Drug Delivery, Cancer, Oncology, Doxorubicin, Liposome, Nanomedicine, Cell
Cryosparc: Accelerated Protein Structure Determination from Cryo-EM 3D imaging, Advanced Health Technologies, Artificial Intelligence (AI), Companies, Drug Discovery, Electron Microscopy, Machine Learning, Pharmaceutical Research / Manufacturing, Pharmaceuticals, Proteins, Research Tools, Software
Lorica Systems: GPU Implementation of RLWE Homomorphic Encryption Companies, Cybersecurity, Electrical and Computer Engineering, Encryption, Software
Detection of Pathogens using Electrochemical Sensing Pathogen, Bacteria, Biosensor, Sensors & Instrumentation, Water, Contamination, Environment
NUAK Inhibitors as Therapeutics for Cancer and Fibrosis Advanced Health Technologies, Biotechnology, Cancer, Cell Signaling, Drug Discovery, Health & Related Life Sciences, Inflammation, Pharmaceuticals, Small Molecules, Therapeutics, Oncology, Fibrosis
An Improved CRISPR-Cas System for Systemic and Combinatorial Genome Wide Screens Advanced Health Technologies, Drug Discovery, Functional Genomics, Gene Editing, Gene Expression, Genetics, Health & Related Life Sciences, molecular mechanisms, Pharmaceutical Research / Manufacturing, Pharmaceuticals, Research Tools, Genetic interactions
Nanoconstructs for Diagnosis and Treatment of Alzheimer’s Disease Alzheimer's disease, Neurological Disorders, Dementia, Therapeutics, Diagnostics, Theranostic, Nanoparticle, Biomedical Imaging, MRI, Biomarkers, Amyloid plaque, Brain
Genetically Engineered Proteins for Diagnosis and Treatment of Crohn’s Disease Crohn's disease, IBD, Inflammatory bowel disease, cytokine, Therapeutics, Diagnostics, Intestine, Immunology
Hi-Efficiency Protection of Linear DNA for Cell Free Protein Synthesis Proteins, Gene Expression, DNA, Cell Free, Protein Syntheis
Micro-robotic Capsule for Drug Delivery and Microbiome Sampling Inflammatory bowel disease, IBD, Crohn's disease, Colitis, Microrobot, Gastrointestinal, Drug Delivery, Therapeutics, Biologics, Sampling
Centivizer: An Interactive, Modular Approach to Dementia Care Companies, Computer Graphics, Computer Hardware, Digital Media, Gaming, Health & Related Life Sciences, Image and video processing, Learning and Memory, Mobile Apps, Neurological Disorders, Patient Care, Smartphones, Software
Assay for Rapid and Sensitive Detection of SARS-CoV-2 Antibodies Covid-19, SARS-COV-2, Immunoassay, Diagnostics, Clinical Tests, Virus
Protein Domains for Controlling Gene Expression CRISPR, gene therapy, gene silencing, repression, gene activation, RNA, interference, KRAB
The Glucose Meter as a Detection System for Point-of-Care Gene Circuit Diagnostics Point-of-Care, Covid-19, Diagnostics, Molecular Detection, Synthetic Biology, SARS-COV-2, Cell Free, Protein Syntheis, Glucose Meter, PCR, Typhoid, Covid-19, Reporter Gene, Virus, Bacteria, Ag Tech, Agriculture, Food Safety, Animal Health
JALI: Automated 3D Lip Synchronization and Facial Animation 3D imaging, Animation, Artificial Intelligence (AI), Companies, Computer Graphics, Software
Glucose-Responsive Microgels and Microneedle Patch to Prevent Hypoglycemia in Diabetics Advanced Health Technologies, Biomaterials, Biotechnology, Medical Devices, metabolic syndromes, Nanomaterials and Nanoparticles, Sensors & Instrumentation, Therapeutics
Immunotyping COVID-19 Patients Using Novel Protein Complementation-Based Assay Covid-19, Diagnostics, Protein-Protein Interactions, Infectious Diseases, Clinical Tests, Pandemic, Immunoassay, SARS-COV-2, Virus, Antibodies
Responsive Antiviral Biomaterials Biomaterials, Companies, Dentistry, Drug Delivery, Medical Implants and Prosthetics, Nanomaterials and Nanoparticles, Covid-19
Rapid, remote vital sign monitoring and screening Advanced Health Technologies, Covid-19, Remote monitoring, Patient Care, Biometrics, Biomedical engineering, Biomedical Imaging, Biosensor, Software, 3D imaging, Image and video processing, Screening
Automatic Learning Filters to Improve the Accuracy of Sensing Algorithms Artificial Intelligence (AI), Machine Learning, Data Analytics, Neural Networks, Wearable Tech, Software, Covid-19, Remote monitoring
Recombinant Antibodies Network (RAN) Antibodies, Cancer, Advanced Health Technologies, Biotechnology, Pharmaceuticals, Therapeutics
Inhibition of PKN1 As Therapy For Chronic Lymphocytic Leukemia (CLL) Advanced Health Technologies, Biotechnology, Cancer, Drug Discovery, Health & Related Life Sciences, Leukemia, Pharmaceuticals, Small Molecules, Therapeutics
Integrated Quantum Dot Barcode Smartphone Optical Device for Diagnosis of COVID-19 Covid-19, Point-of-Care, Nanomaterials and Nanoparticles, Quantum Dots, Portable Diagnostics, Patient Care, Semiconductors, Medical Devices, Cartridge
Integrated Quantum Dot Barcode Smartphone Optical Device for Diagnostics Nanomaterials and Nanoparticles, Patient Care, Point-of-Care, Quantum Dots, Semiconductors, Infectious Diseases, Portable Diagnostics, Medical Devices, Cartridge
Crowdsourced Indoor Localization Using WiFi and Inertial Sensors Indoor Localization, Sensors & Instrumentation, Smart Cities, Smartphones
Electrochemical Antibiotic Susceptibility Testing Device Antibiotics, Bacterial detection, Detection Methods, Electrochemical Detection, Microelectrodes, Microfluidics, Point-of-Care
Novel Substrates for Chemically Defined Culture of Human Pluripotent Stem Cells stem cell culture, pluripotent, Regenerative Medicine, stem cells, tissue culture reagents, Biomaterials
Human Culture Assay to Assess Muscle Stem Cell Potency Regenerative Medicine, stem cells, Stem cell-mediated repair, Muscular Dystrophy, Cell Therapy
Boron Containing Bioactive Biomolecules Chemical Synthesis, Drug Discovery, Health & Related Life Sciences, Pharmaceuticals, Small Molecules, Therapeutics
ODAIA: AI-Driven Customer Journey Intelligence Data Analytics, Artificial Intelligence (AI), Software, Companies, Research Tools
CrossShade: Automated 3D shading from sketches Computer Graphics, Animation, 3D imaging, Software
Selective Enhancement of Electrical Nerve Excitability Artificial Intelligence (AI), Companies, Medical Devices, Medical Implants and Prosthetics, Neurological Disorders
PhenoTips: Software for Patient Phenotyping Companies, Diagnostics, Genetics, Patient Care, Software
System and Methods for Online Socio-Technical Analysis of Buildings Construction, Project Management, Smart Cities, Software
D-PHI: Elastomers for Use with Protein Based Media Regenerative Medicine, Sensors & Instrumentation, Tissue Engineering
CRISPR-Based Screening Platform Technology for Drug Discovery Biotechnology, Cell Signaling, CRISPR, Drug Discovery, Functional Proteomics, Health & Related Life Sciences, Membrane Proteins, Pharmaceutical Research / Manufacturing, Protein-Protein Interactions
Nanoparticles to Enhance Anti-Bacterial Properties and Integrity of Dental Tissue in Root Canal Treatment Dentistry, Nanomaterials and Nanoparticles, Polymers, Root Canal, Antibacterial, Anti-biofilm
Re-PAIR: A CRISPR-Based Technology for Portable Diagnostics & Biotechnology CRISPR, Portable , Diagnostics, Biotechnology, Biosensor, Cell-Free System, Nucleic Acid
Linker-Based Lecithin Microemulsions as Drug Delivery Vehicles Colloids, Complex fluids, Dermal applications, Drug Delivery, Formulation engineering, Cosmeceutical
Portable Automated Manufacturing of Protein-Based Therapeutics Pharmaceutical Research / Manufacturing, Pharmaceuticals, Point-of-Care, Proteins, Regenerative Medicine, Therapeutics
Novel Nematicidal Agents to Improve Crop Production Biotechnology, Health & Related Life Sciences, Crop Sciences, Nematicides
Inducing Directed Migration (Translocation) of Neural Cells Using Electric Fields Medical Devices, Neurological Disorders, Sensory Systems & Rehabilitation
MNAzyme-Based Gold Nanoparticle Sensor Cancer, Diagnostics, Disease Detection, Medical Devices, Nanomaterials and Nanoparticles, Patient Care, Point-of-Care, Sensors & Instrumentation
Mammalian Membrane Two-Hybrid (MaMTH) Technology: a Novel Protein Interaction and Drug Discovery Tool Cancer, Cell Signaling, Disease Detection, Drug Discovery, Genetics, Membrane Proteins, Neurological Disorders, Protein-Protein Interactions, Proteins
Distance Mapping Camera Cameras, Distance Mapping, Indoor Localization, Smart Cities
Solid-state Optical Atomic Clocks Communications, Computer Hardware, Distance Mapping, Navigation, Space
Hybrid Core-Shell Nanoparticles Nanomaterials and Nanoparticles, Polymers, Quantum Dots, Semiconductors
Excimer-Based Molecular Tool for Detection of Proximally Phosphorylated Protein Sites Cancer, Detection Methods, Fluorescent sensors, Proteins, Sensors & Instrumentation
Employing Wayfinding and Bottom-Up Knowledge Discovery and Information Flow in Infrastructure and Construction Projects Construction, Context sensitive design, Knowledge management systems, Project Management, Smart Cities
Automated System for Transforming and Increasing the Intelligibility of Non-Standard Speech Audio, Human-Computer Interaction, Medical Devices, Sensory Systems & Rehabilitation, Software
Microfluidic Devices for Parallel Processes Biomedical engineering, Microfluidics, Polymers
UBA5 Inhibitors for the Treatment of Cancer and Leishmaniasis Cancer, Disease Detection, Drug Discovery, Leukemia, Multiple Myeloma
Robust Floor Detection using Barometer Sensor and WiFi-RSS Indoor Localization, Sensors & Instrumentation, Smart Cities, Smartphones
Multi-Port Converter Structure for DC/DC Power Conversion Automotive, Battery, Energy, Smartphones
Methods for the Prevention and Treatment of Memory Impairment Anesthesia, GABA receptor, Learning and Memory, Neurological Disorders, Point-of-Care
A Method to Improve Memory and Mood by Inhibiting Cell-Surface Expression of Alpha 5 Subunit-Containing GABA-A Receptors Anesthesia, GABA receptor, Genetics, Learning and Memory, Pain, Protein-Protein Interactions
Multimodal Spectroscopy Using a Dielectric Grating Coupled to a Surface Plasmon Resonance Sensor Chips, Circuit design, Computer Hardware, Sensors & Instrumentation, Surface Plasmon Resonance (SPR)
Multiplexed Genetic Detection with Isothermal Signal Amplification Cancer, Chips, Diagnostics, Disease Detection, Genetics, Infectious Diseases, Nanomaterials and Nanoparticles, Point-of-Care, Polymers, Quantum Dots, Smartphones
Nanoparticle-based Thermal Contrast Agents Cancer, Diagnostics, Disease Detection, Infectious Diseases, Nanomaterials and Nanoparticles


  • Market U of T technologies to industry
  • Support the development of startup companies
  • Negotiate license agreements with interested companies
  • Assist in finding partners and funding to support proof-of-concept and commercialization
  • Support long-term relationships with strategic partners that help develop early-stage discoveries into market-ready technologies and products

VPRI Contact


Jennifer Fraser

Director, Innovations
Innovations & Partnerships Office (IPO)
(416) 946-5515